Sheldon Cooper Twin Sister : Melissa missy cooper is sheldon's fraternal twin sister, who is ironically the direct opposite of her brother in many ways (besides being female, she is not above physical confrontation, is very charming and amicable, as well as possessing a very cheeky sense of humor).
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Why Did Mary Cooper Leave The Big Bang Theory Tv Series - Ever since young sheldon started, fans have been wondering why sheldon cooper's older brother other family members who have previously appeared on the show include sheldon's mother (laurie metcalf, who was recently nominated for an oscar for lady bird), his twin sister, missy (courtney.
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